J. W. Athens, M.D. (Assoc.)
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Radioactive diisopropylfluorophosphate (DFP32) has been used to label leukocytes of the granulocytic series in a manner analogous to the labeling of erythrocytes with radioactive sodium chromate. With this technique, the size of the total blood granulocyte pool (TBGP), the distribution of cells therein, and the rate at which granulocytes leave the total blood granulocyte pool, the disappearance rate (T ½), have been measured. From the size of the total blood granulocyte pool and the disappearance rate, the production and destruction rate of granulocytes can be determined. Studies in normal human subjects and in selected patients have demonstrated that leukocytosis and
Athens JW. Leukokinetics.. Ann Intern Med. ;56:684. doi: 10.7326/0003-4819-56-4-684_1
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Published: Ann Intern Med. 1962;56(4):684.
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