S. Sherry, M.D., F.A.C.P.; A. P. Fletcher, M.D.; N. Alkjaersig, M.S.
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As a result of recent studies, it is now apparent that fibrinolysis in man is a dynamic fundamental biological phenomenon, and that aberrations or imbalances in its mechanisms contribute importantly to the pathogenesis of certain clinical disorders. Conceptually, it already has achieved a status comparable to the coagulation mechanism. This report reviews and integrates current information concerning the fibrinolytic process in man, its mechanism of operation under physiological circumstances, and how abnormalities or imbalances in fibrinolytic phenomena contribute to the pathogenesis of certain clinical disorders.
S. Sherry, A. P. Fletcher, N. Alkjaersig. Fibrinolytic Mechanisms.. Ann Intern Med. 1962;56:690. doi: 10.7326/0003-4819-56-4-690_2
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Published: Ann Intern Med. 1962;56(4):690.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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