DANIEL J. MCCARTY JR., M.D.; NORMAN N. KOHN, M.D.; JAMES S. FAIRES, M.D.
The development of a rapid, simple technique for the specific identification of urate crystals in gouty synovial fluid also resulted in the discovery of non-urate crystals in the affected joints of two patients (1). One case displayed the typical clinical features of acute gouty arthritis except for a normal serum urate level. This finding led us to examine microscopically numerous fluids from arthritic joints; we succeeded in finding non-urate crystals in six additional cases. Fluid from one of these patients, a known gouty arthritic, also showed urate crystals. The seven (non-gouty) patients showed clinical and roentgenographic similarities.
Crystals from six
MCCARTY DJ, KOHN NN, FAIRES JS. The Significance of Calcium Phosphate Crystals in the Synovial Fluid of Arthritic Patients: The "Pseudogout Syndrome": I. Clinical Aspects. Ann Intern Med. ;56:711–737. doi: 10.7326/0003-4819-56-5-711
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Published: Ann Intern Med. 1962;56(5_Part_1):711-737.
Hospital Medicine, Rheumatology.
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