FRED B. WESTERVELT JR., M.D.; GEORGE E. SCHREINER, M.D., F.A.C.P.
During the past half century a substantial number of clinical investigators have observed hyperglycemia in patients with renal failure and azotemia (1-3).
The present investigation of this biochemical aberration, termed "azotemic pseudodiabetes," was undertaken with 3 objectives:
1. To reconfirm the existence of impaired glucose tolerance in azotemic subjects;
2. To attempt to characterize the abnormality in a fashion which would be of clinical utility in differentiating true diabetes in an azotemic subject from azotemic pseudodiabetes; and
3. To approach, if possible, a tenable biochemical explanation for its existence.
Hospital staff and patients without metabolic disease served as
WESTERVELT FB, SCHREINER GE. The Carbohydrate Intolerance of Uremic Patients. Ann Intern Med. ;57:266–276. doi: 10.7326/0003-4819-57-2-266
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Published: Ann Intern Med. 1962;57(2_Part_1):266-276.
Hospital Medicine, Nephrology.
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