FRED B. WESTERVELT JR., M.D.; GEORGE E. SCHREINER, M.D., F.A.C.P.
During the past half century a substantial number of clinical investigators have observed hyperglycemia in patients with renal failure and azotemia (1-3).
The present investigation of this biochemical aberration, termed "azotemic pseudodiabetes," was undertaken with 3 objectives:
1. To reconfirm the existence of impaired glucose tolerance in azotemic subjects;
2. To attempt to characterize the abnormality in a fashion which would be of clinical utility in differentiating true diabetes in an azotemic subject from azotemic pseudodiabetes; and
3. To approach, if possible, a tenable biochemical explanation for its existence.
Hospital staff and patients without metabolic disease served as
FRED B. WESTERVELT, GEORGE E. SCHREINER. The Carbohydrate Intolerance of Uremic Patients. Ann Intern Med. 1962;57:266–276. doi: 10.7326/0003-4819-57-2-266
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Published: Ann Intern Med. 1962;57(2_Part_1):266-276.
Hospital Medicine, Nephrology.
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