N. HELLEMANS, M.D.; W. G. R. M. DE BOER, M.D.
Malignant degeneration of a chronic peptic duodenal ulcer is rarely observed, as compared with malignant changes in a peptic ulcer of the stomach. According to Ewing (1), only 10 cases were observed up to 1940. In the same year, Rothaug (2) collected 21 cases of malignant degeneration of duodenal ulcers. On critical evaluation, only 3 cases proved to be adequately documented histologically. These were Rothaug's case of a 74-year-old woman, Ewald's (3) of a woman aged 67, and Kettle's (4) of a man of 68. Pathologists use the same criteria in evaluating such cases as those of malignant degeneration of
HELLEMANS N, DE BOER WGRM. Duodenal Ulcer with Malignant Degeneration. Ann Intern Med. ;57:295–299. doi: 10.7326/0003-4819-57-2-295
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Published: Ann Intern Med. 1962;57(2_Part_1):295-299.
Gastroenterology/Hepatology, Peptic Disease, Peptic Ulcer.
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