LEIGHTON E. CLUFF, M.D.
The seriousness of staphylococcal disease during the past several years has been largely attributable to the emergence of infections caused by staphylococci resistant to available antibacterial drugs. Recently, however, increasing experience with penicillinase-resistant semisynthetic penicillins, such as methicillin and oxacillin, as reported by Simon and Rantz in this issue of the ANNALS, has provided means for the effective drug treatment of almost all severe staphylococcal disease. Nevertheless, there is no evidence and no reason to expect that these antibiotics will reduce significantly the incidence of staphylococcal infection. It is expected that infection will continue to occur, but severe staphylococcal disease
CLUFF LE. Staphylococcal Disease. Ann Intern Med. ;57:499–501. doi: 10.7326/0003-4819-57-3-499
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Published: Ann Intern Med. 1962;57(3):499-501.
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