ROBERT M. DONATI, M.D.; JOHN M. MCCARTHY, M.D.; ROBERT D. LANGE, M.D., F.A.C.P.; NEIL I. GALLAGHER, M.D.
Erythrocythemia has been observed in patients with several types of malignant and non-malignant tumors (1-65). Hematologic remissions following extirpation of the tumor (1-8, 10-14, 29-39, 60, 61) have suggested a causal relationship apparently due to elaboration of an erythropoietic factor by the neoplastic tissue. This report details observations made in 4 patients with erythrocythemia in association with undifferentiated carcinoma of the lung, hepatic cell carcinoma, or renal cell carcinoma. Plasma obtained from 3 of these patients exhibited erythropoietic stimulating activity.
Clinical summaries are recorded below. Only pertinent historical data, physical findings, and diagnostic examinations are included. Results
ROBERT M. DONATI, JOHN M. MCCARTHY, ROBERT D. LANGE, NEIL I. GALLAGHER. Erythrocythemia and Neoplastic Tumors. Ann Intern Med. 1963;58:47–55. doi: 10.7326/0003-4819-58-1-47
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Published: Ann Intern Med. 1963;58(1):47-55.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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