LARKIN M. WILSON, M.D.
The occurrence, prognosis, and clinical course of many severe bacterial infections have been greatly improved with the development of effective antimicrobial agents. There is well-documented evidence that with these drugs has come a change in bacterial flora within the population, as well as an alteration in the etiologic organisms of several specific infectious entities (1-3).
In view of this shift in etiology, it would seem reasonable to ask if there has been a corresponding change in the pathology of the specific infectious diseases since the introduction of antibiotics. Kneeland and Price have shown that the organisms formerly considered to be
WILSON LM. Pathology of Fatal Bacterial Endocarditis before and since the Introduction of Antibiotics. Ann Intern Med. ;58:84–92. doi: 10.7326/0003-4819-58-1-84
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Published: Ann Intern Med. 1963;58(1):84-92.
Cardiology, Endocarditis, Infectious Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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