FRANCISCO M. GONZALEZ, M.D.; G. LENNARD GOLD, M.D.; BRUCE I. SHNIDER, M.D., F.A.C.P.
The occurrence of spontaneous hypoglycemia in association with large non-pancreatic tumors has been described in the medical literature by several investigators (1, 2). This type of hypoglycemia is indistinguishable from the organic variety that accompanies islet cell tumors of the pancreas or severe hypo-adrenalism (3). The tumors reported have been of mesenchymal origin and sarcomatous in type. Also, adrenocortical carcinomas have been known to occasionally produce a lowering of blood sugar values (3), but these neoplasms, too, originate from mesodermal tissue. Reports appearing in the past (4-7) have conveyed the impression that hypoglycemia is exclusively a function of tumors of
GONZALEZ FM, GOLD GL, SHNIDER BI. Gastrointestinal Carcinoma and Concomitant Hypoglycemia. Ann Intern Med. 1963;58:149–154. doi: 10.7326/0003-4819-58-1-149
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Published: Ann Intern Med. 1963;58(1):149-154.
Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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