CLARK H. MILLIKAN, M.D., F.A.C.P.
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Fazekas, Alman, and Sullivan in their paper "Prognostic Uncertainties in Cerebral Vascular Disease," in this issue of the ANNALS, report data obtained in the careful clinical and laboratory investigation of 25 patients with aortocranial disease; 12 had arterial surgery while 13 did not, and all patients were treated with anticoagulants. Their observations exemplify a number of the complex unsolved problems that hamper the clinician in the diagnosis and treatment of occlusive cerebral vascular disease. Although intracranial or extracranial atherosclerosis of cerebral vessels (or both) appears to be the basic pathologic change associated with clinical findings of focal cerebral ischemia, severe
MILLIKAN CH. Perplexities in Cerebrovascular Disease. Ann Intern Med. ;58:191–192. doi: 10.7326/0003-4819-58-1-191
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Published: Ann Intern Med. 1963;58(1):191-192.
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