J. ALLAN HOBSON, M.D.; JOSEPH T. ENGLISH, M.D.
Reports of "self-induced" water intoxication (1-5) vary with experimental evidence of difficulty in producing the state in normal individuals (6). In view of the occurrence of abnormal water metabolism in some mentally ill patients (7, 8), it is of interest to note the high prevalence of pre-existing psychiatric disorder in patients with self-induced water intoxication (1-5, 9). Since predisposition to development of the syndrome has been shown to be associated with various other disease states (10-15), where is is attributable to well-known mechanisms, the operation of some such mechanism in the patients with mental disease who develop water intoxication should
HOBSON JA, ENGLISH JT. Self-induced Water Intoxication: Case Study of a Chronically Schizophrenic Patient with Physiological Evidence of Water Retention Due to Inappropriate Release of Antidiuretic Hormone. Ann Intern Med. ;58:324–332. doi: 10.7326/0003-4819-58-2-324
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Published: Ann Intern Med. 1963;58(2):324-332.
Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology.
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