H. R. Holman, M.D.
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The ability to exchange normal tissues for diseased tissues will greatly enhance the therapeutic capabilities of the physician. Surgical problems associated with tissue transplantation have been largely resolved. Modern methods of tissue and organ storage promise to solve the problem of supply of transplantable materials. The major impediment to successful tissue transplantation, the immunological rejection of the graft by the host, remains.
Rejection of grafts can be prevented by destroying the immune responses of the host with radiation, radiomimetic drugs, or other chemical means. Graft rejection can be avoided by grafting between genetically identical individuals; it can be precluded by
Holman HR. Homograft Survival.. Ann Intern Med. ;58:736–737. doi: 10.7326/0003-4819-58-4-736_3
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Published: Ann Intern Med. 1963;58(4):736-737.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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