FELICE MANFREDI, M.D.; DAVID ROSENBAUM, M.D.; ROY H. BEHNKE, M.D.
Percutaneous needle biopsy of pulmonary tissue has been used in the past for the bacteriologic study of acute pneumonic processes (1, 2) or for tissue diagnosis of an isolated intrathoracic mass adjacent to the chest wall (3-6). There is a widely held opinion that needle lung biopsy in diffuse pulmonary disease is often followed by complications such as pneumothorax, pulmonary hemorrhage, or spread of the disease process into the chest wall through the fistulous tract, and is thus contraindicated; in addition, this procedure has been thought not to provide tissue adequate for diagnostic studies (7). Lung biopsy by conventional thoracotomy
MANFREDI F, ROSENBAUM D, BEHNKE RH. Percutaneous Needle Biopsy of the Lung in Diffuse Pulmonary Diseases. Ann Intern Med. 1963;58:773–788. doi: 10.7326/0003-4819-58-5-773
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Published: Ann Intern Med. 1963;58(5):773-788.
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