LAURENCE J. MCCARTHY, M.D.; JACK L. TITUS, M.D., PH.D.; GUY W. DAUGHERTY, M.D., F.A.C.P.
The nephrotic syndrome may be defined as a clinical state resulting from a renal disorder and characterized by edema, hyperlipemia, hypoproteinemia, and massive proteinuria. The underlying renal condition may be any one of several disease processes (1-7), including thrombosis of both renal veins. Harrison, Milne, and Steiner (8) recognized 4 etiologic varieties of renal-vein thrombosis:  thrombosis of the inferior vena cava and renal veins secondary to extension of thrombi from pelvic or leg veins;  thrombotic occlusion of the inferior vena cava secondary to invasion by a malignant neoplasm, especially hypernephroma, or to external compression by tumor;  renal-vein
LAURENCE J. MCCARTHY, JACK L. TITUS, GUY W. DAUGHERTY. Bilateral Renal-vein Thrombosis and the Nephrotic Syndrome in Adults. Ann Intern Med. 1963;58:837–857. doi: 10.7326/0003-4819-58-5-837
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Published: Ann Intern Med. 1963;58(5):837-857.
Nephrology, Nephrotic Syndrome.
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