A. H. TOFFLER, M.D.; P. B. HUKILL, M.D.; H. M. SPIRO, M.D., F.A.C.P.
Extensive brown pigmentation of the muscular layer of the small bowel is uncommon, although such discoloration of the gastrointestinal tract has been recorded in isolated case reports for the past 20 years (1-12). We recently studied a patient with extensive brown pigmentation of the small intestine. The picture he presented was not recognized by us or by our colleagues in this or several other cities, and most often was considered a form of melanosis coli. Our report proposes to review the clinical and pathologic pattern of this "brown bowel" syndrome.
A 50-year-old man entered the Grace-New Haven Community
TOFFLER AH, HUKILL PB, SPIRO HM. Brown Bowel Syndrome. Ann Intern Med. ;58:872–877. doi: 10.7326/0003-4819-58-5-872
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Published: Ann Intern Med. 1963;58(5):872-877.
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