W. P. BEETHAM JR., M.D.; R. L. KAYE, M.D.; H. F. POLLEY, M.D.
Charcot's classic description of clinical, anatomic, and pathologic changes in various joints associated with locomotor ataxia (tabes dorsalis) was published in 1868 (1), and to this day, his name and description remain identified with neuropathic joint disease. Arthropathy of the type described by Charcot has also been associated with various other conditions, but is most often attributed to either tabes (2, 3) or diabetes mellitus (4, 5). Other reported instances of neuropathic arthropathy have been attributed to syringomyelia (2, 6), injury to nerve roots (7), degenerative changes in the spinal cord due to pernicious anemia (8), spina bifida (9), congenital
W. P. BEETHAM, R. L. KAYE, H. F. POLLEY. Charcot's Joints: A Case of Extensive Polyarticular Involvement, and Discussion of Certain Clinical and Pathologic Features. Ann Intern Med. 1963;58:1002–1012. doi: 10.7326/0003-4819-58-6-1002
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Published: Ann Intern Med. 1963;58(6):1002-1012.
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