Pregnancy may be considered as a diabetogenic event which is nevertheless survived without apparent diabetes by the great majority of women. The mechanism of this tendency toward diabetes is unknown although it is presumed to be the result of hormonal influences. Whether or not abnormalities of carbohydrate tolerance appear probably depends on the functional state of the islands of Langerhans prior to conception; normal islands meet the demand of pregnancy but functionally inadequate islets cannot, and hyperglycemia supervenes.
STANDARD GLUCOSE TOLERANCE TESTS
Some (1-5) who have employed intravenous glucose tolerance tests
Diabetes and Pregnancy. Ann Intern Med. ;59:1–82. doi: 10.7326/0003-4819-59-1-1_1
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Published: Ann Intern Med. 1963;59(1_Part_2):1-82.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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