JAMES R. MCPHERSON, M.D.; JOHN L. JUERGENS, M.D.; RAY W. GIFFORD JR., M.D.
Thromboangiitis obliterans (Buerger's disease) has been defined as a segmental, inflammatory, occlusive disease which primarily affects small or medium-sized arteries and veins in the extremities of young adults, usually males (1). The most frequent clinical manifestation of thromboangiitis obliterans is ischemia of one or both feet with greatly diminished or absent pedal pulsations; the proximal arterial pulsations are usually normal during the early stages of the disease. There is often evidence of ischemia of one or more fingers, and episodes of recurrent segmental thrombophlebitis of superficial nonvaricose veins of the extremities may occur. Almost always there appears to be a
MCPHERSON JR, JUERGENS JL, GIFFORD RW. Thromboangiitis Obliterans and Arteriosclerosis Obliterans: Clinical and Prognostic Differences. Ann Intern Med. ;59:288–296. doi: 10.7326/0003-4819-59-3-288
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Published: Ann Intern Med. 1963;59(3):288-296.
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