MORTIMER J. LACHER, M.D.; LEON N. SUSSMAN, M.D.
Although we can now look back upon 131 years of contemplation, speculation, and experimentation since Hodgkin's (1) first description of the disease that now bears his name, our knowledge of the true nature of the disease has not been increased materially.
The following questions that Dameshek (2) asked in 1933 regarding Hodgkin's disease are pertinent today because they still remain unanswered: "Is it infectious or malignant in nature?" (Of course, with the revival of the virus theory in the etiology of cancer, it may be both infectious and malignant in nature.) "Is the type cell of lymphoid or reticuloendothelial origin?"
LACHER MJ, SUSSMAN LN. Leukemia and Hodgkin's Disease. Ann Intern Med. ;59:369–378. doi: 10.7326/0003-4819-59-3-369
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Published: Ann Intern Med. 1963;59(3):369-378.
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