HUBERT I. CAPLAN, M.D.
A number of serologic procedures have been developed in recent years in the search for a diagnostic test for rheumatoid arthritis, for example, latex fixation tests. None of these have proved to be highly sensitive and, at the same time, specific for rheumatoid arthritis. This is not surprising since the very factors tested are generally nonspecific macroglobulins. In addition, until its cause and pathogenesis are known, rheumatoid arthritis cannot be defined precisely.
The use of latex fixation tests in other medical problems has received little attention. It is the purpose of this report to describe some of these uses in
CAPLAN HI. The Use of Latex Fixation Tests in Non-rheumatic States. Ann Intern Med. ;59:449–454. doi: 10.7326/0003-4819-59-4-449
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Published: Ann Intern Med. 1963;59(4):449-454.
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