J. H. PHILLIPS, M.D.; G. E. BURCH, M.D., F.A.C.P.; N. P. DE PASQUALE, M.D.
Recently 2 patients have been reported with clinical manifestations of mitral valve insufficiency, in whom subsequent autopsy findings strongly suggested that papillary muscle dysfunction secondary to myocardial infarction was the underlying cause (1). Evidence was offered to support the contention that mechanical dysfunction of the papillary muscle may result in a murmur of mitral incompetence with characteristics distinctive enough to aid in its clinical recognition. The characteristic
auscultatory finding is a systolic murmur, loudest at the apex, with delayed onset after the first heart sound and with a tendency to an "ejection" or "diamond-shaped" configuration (Figure 1). The most important
PHILLIPS JH, BURCH GE, DE PASQUALE NP. The Syndrome of Papillary Muscle Dysfunction: Its Clinical Recognition. Ann Intern Med. ;59:508–520. doi: 10.7326/0003-4819-59-4-508
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Published: Ann Intern Med. 1963;59(4):508-520.
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