HUGH A. EDMONDSON, M.D., F.A.C.P.; ROBERT L. PETERS, M.D.; TELFER B. REYNOLDS, M.D., F.A.C.P.; OLIVER T. KUZMA, M.D.
In recent years we have observed a group of alcoholic patients who present a symptom complex accompanied by a distinctive morphologic lesion in the hepatic cells that has been known as alcoholic hyalin or "Mallory bodies." This morphologic change was first described by Mallory in 1911 (1) and further elucidated by numerous pathologists (2-7). However, the recognition of a clinical syndrome associated with it came much later, Phillips and Davidson (8) first calling attention to "acute hepatic insufficiency of the chronic alcoholic" in 1954. A few publications pertaining to the disorder have appeared since 1954. Such terms as florid cirrhosis
HUGH A. EDMONDSON, ROBERT L. PETERS, TELFER B. REYNOLDS, OLIVER T. KUZMA. Sclerosing Hyaline Necrosis of the Liver in the Chronic Alcoholic: A Recognizable Clinical Syndrome. Ann Intern Med. 1963;59:646–673. doi: 10.7326/0003-4819-59-5-646
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Published: Ann Intern Med. 1963;59(5_Part_1):646-673.
Gastroenterology/Hepatology, Liver Disease.
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