NORMAN KRASNOW, M.D.; RICHARD GORLIN, M.D.
Characterization of coronary insufficiency has improved significantly in the last 20 years. In addition to clarification of the diverse clinical syndromes (1, 2), diagnostic abnormalities both in the resting and in the stress electrocardiogram have been carefully documented. Recently, the introduction of coronary arteriography has permitted visualization of the diseased vessels during life (3). On the other hand, relatively little attention has been paid to the functional or physiologic aspects of the syndrome as it affects the myocardium.
Abnormalities in hemodynamics in subjects with coronary insufficiency have been described previously (4, 5). Studies from this laboratory have suggested that the
KRASNOW N, GORLIN R. Myocardial Lactate Metabolism in Coronary Insufficiency. Ann Intern Med. ;59:781–787. doi: 10.7326/0003-4819-59-6-781
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Published: Ann Intern Med. 1963;59(6):781-787.
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