R. R. SCHUMACHER, M.D.; A. S. RIDOLFO, PH.D., M.D.; B. L. MARTZ, M.D., F.A.C.P.
The properties of the peritoneum as a dialyzing membrane were first explored as early as 1894 to 1895 (1, 2). Subsequent work enlarged upon this early knowledge and demonstrated that:  fluids injected into the peritoneal cavity would change in volume over a short period of time according to the concentration and nature of solutes in the dialyzing fluid (3-7); and  various substances would cross the peritoneum in response to concentration gradients (3, 4, 7-11). It was demonstrated that urea, uric acid, creatinine, and sulfate, as well as chlorbutanol, salicylates, and phenolphthalein (7) would migrate into fluids injected into
SCHUMACHER RR, RIDOLFO AS, MARTZ BL. Periodic Peritoneal Dialysis for Chronic Renal Failure: A Case Study of Sixteen Months' Experience. Ann Intern Med. ;60:296–305. doi: 10.7326/0003-4819-60-2-296
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Published: Ann Intern Med. 1964;60(2_Part_1):296-305.
Chronic Kidney Disease, Nephrology, Renal Replacement Therapy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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