NORMAN H. BELL, M.D.; FREDERIC C. BARTTER, M.D.
Calcium absorption is excessive in some patients with sarcoidosis and hypercalciuria and can be reversed with carbohydrate-active steroids (1-3) and enhanced with small doses of vitamin D (4-6). The abnormality of calcium metabolism was found to result from hypersensitivity to vitamin D (1, 3-6) and not from hypervitaminosis D (2). It has also been shown that the defect in calcium absorption in patients with renal failure is characterized by decreased absorption of calcium and probably by diminished responsiveness to vitamin D as well (7-9).
This report describes a patient with sarcoidosis and abnormally increased absorption of calcium who developed glomerulonephritis
BELL NH, BARTTER FC. Transient Reversal of Hyperabsorption of Calcium and of Abnormal Sensitivity to Vitamin D in a Patient with Sarcoidosis During Episode of Nephritis. Ann Intern Med. ;61:702–710. doi: 10.7326/0003-4819-61-4-702
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Published: Ann Intern Med. 1964;61(4):702-710.
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