Domingo M. Aviado, M.D.
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The use of drugs to treat shock is based on one or more of the following types of actions: vasoconstriction, cardiac stimulation, and reversal of some of the vicious cycles in the production of shock. There are four groups of drugs useful in the treatment of shock.
1. Predominately vasoconstrictors, such as angiotensin, methoxamine, and phenylephrine. The last two are sympathomimetic drugs with pure vasoconstrictor action. The major hemodynamic pattern accompanying the rise in systemic blood pressure is an elevation in total systemic vascular resistance but a fall in cardiac output. Levarterenol, although a predominant vasoconstrictor, can potentially stimulate the
Aviado DM. The Pharmacology of Sympathomimetic and Blocking Drugs in the Treatment of Shock.. Ann Intern Med. ;61:797–798. doi: 10.7326/0003-4819-61-4-797_2
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Published: Ann Intern Med. 1964;61(4):797-798.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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