PAUL R. MCCURDY, M.D.
Although the majority of patients with iron deficiency anemia can be treated adequately with oral iron compounds, it is occasionally necessary to resort to parenteral medication. The indications for administering iron by injection include chronic bleeding with a need for rapid repletion of stores, malabsorption of iron from the gastrointestinal tract, and intolerance of oral iron compounds. Despite the definite need for a parenteral iron medication, an entirely suitable and safe injectable preparation has not been developed.
Initial attempts at therapy with ionizable iron salts led to serious reactions. Subsequently, poorly ionizable complexes have been examined for their clinical usefulness.
MCCURDY PR. Parenteral Iron Therapy: II: A New Iron-sorbitol Citric Acid Complex for Intra-muscular Injection. Ann Intern Med. 1964;61:1053–1064. doi: 10.7326/0003-4819-61-6-1053
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Published: Ann Intern Med. 1964;61(6):1053-1064.
Emergency Medicine, Hematology/Oncology, Hospital Medicine, Nephrology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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