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If study of the usual course of disease is the warp, the differential analysis of clinical manifestations is the woof of clinical medicine. Most American textbooks of medicine (and medical students) are oriented toward the former aspect and present in monographic style, etiology, pathology, diagnosis, treatment, and prognosis. The fourth edition of this multiple author book, on the other hand, evaluates in 35 chapters the major signs and symptoms encountered in practice. In each chapter an important sign or symptom is examined for the various factors in its causation. For those readers indoctrinated in the more conventional longitudinal view of
Signs and Symptoms. Applied Pathologic Physiology and Clinical Interpretation. Ann Intern Med. ;62:181. doi: 10.7326/0003-4819-62-1-181_1
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Published: Ann Intern Med. 1965;62(1):181.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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