PETER BOWEN, M.D.; CATHERINE S. N. LEE, M.D.; CLAUDE J. MIGEON, M.D.; NORMAN M. KAPLAN, M.D.; PEGGY J. WHALLEY, M.D.; VICTOR A. MCKUSICK, M.D., F.A.C.P.; EDWARD C. REIFENSTEIN JR., M.D., F.A.C.P.
The subject of this report is a syndrome of abnormal sexual development in the male that is simply inherited and consists of varying degrees of hypospadias associated with a characteristic type of hypogonadism. Two of the three families investigated were previously reported in brief by Reifenstein (1) and Young (2). The third family, living in Texas, has not been previously studied. Similar families have been described by Peters, Sieber, and Davis (3) and by Gilbert-Dreyfus, Sébaoun, and Belaisch (4). In the account that follows, complete details of the clinical characteristics, testicular histology, endocrine findings, and chromosome status of affected individuals
BOWEN P, LEE CSN, MIGEON CJ, KAPLAN NM, WHALLEY PJ, MCKUSICK VA, et al. Hereditary Male Pseudohermaphroditism with Hypogonadism, Hypospadias, and Gynecomastia: (Reifenstein's Syndrome). Ann Intern Med. ;62:252–270. doi: 10.7326/0003-4819-62-2-252
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Published: Ann Intern Med. 1965;62(2):252-270.
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