ROGER K. LARSON, M.D., F.A.C.P.; RICHARD GORDINIER, M.D.
Beginning with the initial description by Rosen, Castleman, and Liebow (1), a total of 79 cases of pulmonary alveolar proteinosis has been recorded in the medical literature (1-51). It is the purpose of this paper to add 6 new cases, to summarize the clinical features of all 85 cases, and to formulate a new theory about the origin of the intra-alveolar material that is so characteristic of the disease. Eighty-four of these 85 cases were confirmed by histological examination. One diagnosis was based on sputum examination only (25).
W. H., a 38-year-old Caucasian male police officer,
LARSON RK, GORDINIER R. Pulmonary Alveolar Proteinosis: Report of Six Cases, Review of the Literature, and Formulation of a New Theory. Ann Intern Med. ;62:292–312. doi: 10.7326/0003-4819-62-2-292
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Published: Ann Intern Med. 1965;62(2):292-312.
Hospital Medicine, Lupus Erythematosus, Rheumatology.
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