JAMES B. WYNGAARDEN, M.D.; R. WAYNE RUNDLES, M.D.; EARL N. METZ, M.D.
Elsewhere in this journal appear four papers on various aspects of gout. One by Malawista and Seegmiller represents a further study on the role of crystals of sodium urate in the pathogenesis of the acute attack, and of the effect of colchicine upon the inflammatory process. A second paper by Kaplan, Bernstein, Wallace, and Halberstam reports the presence of hyperamino-acidemia in hyperuricemic subjects and raises some questions concerning the fundamental metabolic disturbance of primary gout. A third paper by Gonick, Rubini, Gleason, and Sommers adds to our knowledge and mystery about the nature of the renal complications of gout. A
WYNGAARDEN JB, RUNDLES RW, METZ EN. Allopurinol in the Treatment of Gout. Ann Intern Med. ;62:842–847. doi: 10.7326/0003-4819-62-4-842
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Published: Ann Intern Med. 1965;62(4):842-847.
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