STANTON SEGAL, M.D.
Within recent years authorities on cystinuria have concluded that renal clearance evidence has clarified the pathogenesis of this hereditary disease (1, 2). The National Institutes of Health (NIH) Clinical Staff Conference on cystinuria in this issue of the ANNALS is an excellent example of how the application of new investigative techniques and illuminated thought can make a seemingly well-understood disease the subject of fruitful research. The use of D-penicillamine to prevent cystine stone formation not only provides useful therapy but will, no doubt, further the insight into the underlying defect as a result of investigative efforts to understand some of
SEGAL S. Disorders of Amino Acid Transport. Ann Intern Med. ;62:847–851. doi: 10.7326/0003-4819-62-4-847
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Published: Ann Intern Med. 1965;62(4):847-851.
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