To the Editor: "Primum non nocere," in an editorial [ANNALS, December, 1964] which is, in the main, a statement on the use of a single chemical rather than a balanced evaluation of reports for and against its use, might be interpreted as a strong deterrent to the use of any "new" drug and is in direct contrast to the publication of reports of intracardiac catheterization involving puncture of the interauricular septum and of many other procedures by internists which involve a "calculated risk" (including the use of penicillin).
I share Dr. Rothermich's qualms over the use of antimalarial drugs in
CHLOROQUINE IN RHEUMATOID ARTHRITIS. Ann Intern Med. ;62:1065–1067. doi: 10.7326/0003-4819-62-5-1065
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Published: Ann Intern Med. 1965;62(5):1065-1067.
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