Dean T. Mason, M.D.; Eugene Braunwald, M.D., F.A.C.P.
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In spite of the widespread use of amyl nitrite and nitroglycerin in clinical medicine as therapeutic agents and diagnostic aids, the mode of action of these drugs on the circulation remains to be defined. To determine their actions on the arterial and venous beds of the forearm in normal man, forearm blood flow was measured with a strain-gauge plethysmograph and forearm vascular resistance was calculated. Venous tone was estimated after venous occlusion of the upper arm by an acute occlusion technique and by an equilibration technique in which changes in forearm volume were assessed at constant forearm venous pressure. In
Mason DT, Braunwald E. The Effects of Amyl Nitrite and Nitroglycerin on the Arterial and Venous Beds in Man.. Ann Intern Med. ;62:1069–1070. doi: 10.7326/0003-4819-62-5-1069_3
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Published: Ann Intern Med. 1965;62(5):1069-1070.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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