H. G. Williams-Ashman, Ph.D.
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By now an immense amount is known concerning the relationship of the chemical structure of androgens, estrogens, and gestagens to the responses they elicit in various bio-assay systems. And it appears that the major metabolic transformations undergone by sex hormones in the living organism have been mapped. But it still is not possible to provide a comprehensive explanation in molecular terms for the major biological actions of any single mammalian sex hormone. A brief account will be given of three recent types of experimental approach to this problem: (1) Studies on the ability of sex hormones to mediate the transfer
Williams-Ashman HG. Experimental Approaches to the Molecular Basis of Sex Hormone Action.. Ann Intern Med. ;62:1076. doi: 10.7326/0003-4819-62-5-1076_1
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Published: Ann Intern Med. 1965;62(5):1076.
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