Thomas J. Lord, M.D.; C. Conrad Johnston Jr., M.D.; Norman J. Lavy, M.D.; A. Donald Merritt, M.D., F.A.C.P.; William P. Deiss Jr., M.D., F.A.C.P.
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Thirty-six patients in two families were studied roentgenographically for evidence of osteopetrosis. Eleven patients (five males, and six females) were found to have changes typical of the disease. In ten patients with osteopetrosis, acid phosphatase levels were elevated as compared with normal values found in the remainder of both families. Fractures were the most common clinical manifestation of the disease, with four males having a total of 44 fractures, and two females with a total of 6. Optic atrophy occurred in one male. Osteomyelitis occurred in one male in our series, and there was good evidence of this also being
Lord TJ, Johnston CC, Lavy NJ, Merritt AD, Deiss WP. Osteopetrosis: A Clinical and Metabolic Study.. Ann Intern Med. 1965;62:1078. doi: 10.7326/0003-4819-62-5-1078_1
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Published: Ann Intern Med. 1965;62(5):1078.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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