Steven L. Merrill, M.D.; Sydney M. Finegold, M.D., F.A.C.P.; Bernard Smolens, M.D.; Alvin Davis, M.D.
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Cephalothin is a new semisynthetic antibacterial agent structurally related to the penicillins. It is effective against penicillinase-producing staphylococci as well as other gram-positive and gram-negative organisms. More than 300 patients have been treated with cephalothin in this hospital over the past 2 years. Thirty-three of these patients were judged to have life-threatening infections, and the present report is concerned with these cases.
Twenty-three patients with well-documented pneumonia caused by Staphylococcus aureus received cephalothin in doses ranging from 2 to 6 grams intramuscularly for periods from 7 to 82 days. The patients were all males, the mean age being 64. All
Merrill SL, Finegold SM, Smolens B, Davis A. The Use of Cephalothin1 in the Treatment of Serious Infections.. Ann Intern Med. ;62:1091–1092. doi: 10.7326/0003-4819-62-5-1091_3
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Published: Ann Intern Med. 1965;62(5):1091-1092.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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