Norman M. Kaplan, M.D., F.A.C.P.; Jack G. Silah, M.D.; Warren E. Goorno, M.D.
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The pressor response to intravenous angiotensin II has been measured in patients with various hypertensive diseases, including renovascular hypertension, primary aldosteronism, pheochromocytoma, and coarctation of the aorta. The procedure has been of value in solving the following clinical problems: (1) Establishing whether renal vascular lesions are the cause of renovascular hypertension. More angiotensin has been required to induce a 20 mm Hg rise in diastolic blood pressure in all 24 patients with functionally significant renovascular disease than in any patient with essential hypertension (135 patients) or hypertension associated with chronic renal parenchymal disease (32 patients). Nine patients with renal vascular
Kaplan NM, Silah JG, Goorno WE. The Angiotensin Infusion Test in the Differential Diagnosis of Curable Hypertension.. Ann Intern Med. 1965;62:1095. doi: 10.7326/0003-4819-62-5-1095_1
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Published: Ann Intern Med. 1965;62(5):1095.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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