This content is PDF only. Please click on the PDF icon to access.
Four leading authorities in the field present in five chapters a composite and comprehensive coverage of our enlarged understanding of Tay-Sachs' disease.
Leading on from an historical account of the disease, the clinical features are described. It is stressed that affected infants do not in fact appear normal during the first 4 to 6 months of life but that the characteristic motor response to sound can be elicited within a few weeks of birth. Pathogenesis and evolution are traced through gross and histologic anatomy and more clearly delineated with the refinements of histochemistry and electron microscopy. Of special interest is
Tay-Sachs' Disease.. Ann Intern Med. ;62:1104. doi: 10.7326/0003-4819-62-5-1104_1
Download citation file:
Published: Ann Intern Med. 1965;62(5):1104.
Copyright © 2018 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use