M. LEWIS, M.D.; G. R. LEE, M.D.; A. HAUT, M.D.
Hemochromatosis occurs frequently in the course of thalassemia major (1). On the other hand, it is most unusual to encounter this complication in patients with thalassemia minor. In fact, the case report of Etienne-Martin, Klepping, and Binet (2) is the only one in which adequate pathological, biochemical, and genetic evidence for both hemochromatosis and thalassemia minor is presented.
The present report concerns a patient with thalassemia minor who developed severe hemochromatosis resulting in his death. Of further interest is the observation that anemia became pronounced as iron loading developed.
Patient G. N., a 61-year-old white male, was admitted
M. LEWIS, G. R. LEE, A. HAUT. The Association of Hemochromatosis with Thalassemia Minor. Ann Intern Med. 1965;63:122–128. doi: 10.7326/0003-4819-63-1-122
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Published: Ann Intern Med. 1965;63(1):122-128.
Hematology/Oncology, Red Cell Disorders.
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