ROBERT A. FISHMAN, M.D.
The diagnostic value of lumbar puncture was established in the early years of this century with particular reference to the changes in the cellular and chemical constituents of the fluid. A reduced concentration of glucose was recognized as characteristic of purulent meningitis and, subsequently, hypoglycorrhachia was also noted to occur with a variety of meningeal disorders, including tuberculous, fungal, and luetic meningitis, subarachnoid hemorrhage, meningeal sarcoidosis, and carcinomatosis. In this issue of the ANNALS OF INTERNAL MEDICINE, Kim and Resnick report two additional cases in which the diagnosis of carcinomatous meningitis could be made when marked depression of the cerebrospinal
FISHMAN RA. Carrier Transport and the Concentration of Glucose in Cerebrospinal Fluid in Meningeal Diseases. Ann Intern Med. 1965;63:153–155. doi: 10.7326/0003-4819-63-1-153
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Published: Ann Intern Med. 1965;63(1):153-155.
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