THOMAS R. RILEY, M.D.; RALPH G. WIELAND, M.D.; JOHN MARKIS, B.A.; GEORGE J. HAMWI, M.D., F.A.C.P.
Otto Werner (1), as a medical student at the Ophthalmology Clinic in Kiel, studied four siblings with cataracts and scleroderma whom he described in 1904 in his doctoral dissertation. In 1868, Rothmund (2) had reported three families whose members were afflicted with cataracts and a peculiar telangiectatic dermatological condition. The similarity between these syndromes resulted in considerable confusion, and for years investigators did not distinguish one from the other. In 1934, Oppenheimer and Kugel (3) described for the first time in the American literature two patients similar to those of Werner. They emphasized the difference between these patients and those
RILEY TR, WIELAND RG, MARKIS J, HAMWI GJ. Werner's Syndrome. Ann Intern Med. 1965;63:285–294. doi: 10.7326/0003-4819-63-2-285
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Published: Ann Intern Med. 1965;63(2):285-294.
Hospital Medicine, Neurology.
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