Cyrus Afrasiabi, M.D.; James L. Whitehouse, M.S.; Edwin M. Knights Jr., M.D., F.A.C.P.
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A new, highly sensitive liver function test has been developed to aid the clinical laboratory in providing information for the physician for the evaluation of the status of the liver. This test is based on measurement of serum guanase. Guanase, which participates in purine metabolism, is present in high concentration in the liver, but normally only negligible amounts can be found in the blood; thus it can provide an indication of the extent of liver cell damage by its concentration in serum of plasma.
To be practical as a liver function test, a procedure must be easily performed by the
Afrasiabi C, Whitehouse JL, Knights EM. Clinical Applications of Serum Guanase Determinations.. Ann Intern Med. ;63:909. doi: 10.7326/0003-4819-63-5-909_3
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Published: Ann Intern Med. 1965;63(5):909.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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