Martin M. Nothman, M.D.; Allan D. Callow, M.D.
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Values for serum and urinary diastase do not change after subtotal pancreatectomy in man and after complete extirpation of the gland in dogs. When the pancreatic ducts are ligated these enzymes become markedly increased. They rise further when secretin is injected. They fall to their original values when the pancreas is removed after duct ligation. The same effect is obtained by establishment of a pancreatic fistula after ligation: both diastases return to their original levels. Secretin given after performance of the fistula does not affect the values for diastase in serum or urine. But the amount of diastase secreted through
Nothman MM, Callow AD. Investigations on the Source of Diastase in Serum and Urine.. Ann Intern Med. ;63:910. doi: 10.7326/0003-4819-63-5-910_1
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Published: Ann Intern Med. 1965;63(5):910.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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