Spencer Raab, M.D.; Miriam Dahlke, M.D.
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The treatment of multiple myeloma with agents such as radioactive phosphorus, urethane, corticosteroids, etc., has been most discouraging. Recently, the use of cyclophosphamide has resulted in some prolongation of survival in this disease. In addition, L-phenylalanine mustard (melphalan) has also been shown to be associated with an initial improvement in some patients. This study was undertaken to assess the value of continuous mainentance therapy with this drug for the life of the patient.
All patients in whom the diagnosis of multiple myeloma was made in the past 12 months at the Philadelphia General Hospital and on the wards at the
Raab S, Dahlke M. The Treatment of Multiple Myeloma and Macroglobulinemia of Waldenstrom with the Continuous Administration of L-Phenylalanine Mustard.. Ann Intern Med. 1965;63:913. doi: 10.7326/0003-4819-63-5-913_1
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Published: Ann Intern Med. 1965;63(5):913.
Hematology/Oncology, Multiple Myeloma.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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