Kaye H. Kilburn, M.D.
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Confusion, asterixis, and tremors have been noted previously in patients with chronic respiratory insufficiency, but the incidence and importance of these signs has received little attention. Cognitive dysfunction, memory deficits, disorientation, somnolence, coma, asterixis, tremors, headache, and seizures were appraised and correlated with cardiopulmonary features and arterial blood hydrogen ion concentration (pH), carbon dioxide (Paco2), and oxygen (Pao2) tensions during 32 episodes of acute respiratory failure. This syndrome was defined by a Paco2 above 60 mm Hg or a Pao2 below 55 mm Hg. Twenty-two patients had asterixis, 20 had somnolence, 16 had cognitive dysfunction, memory deficits and inability to
Kilburn KH. Neurologic Manifestations of Respiratory Failure.. Ann Intern Med. 1965;63:919–920. doi: 10.7326/0003-4819-63-5-919_3
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Published: Ann Intern Med. 1965;63(5):919-920.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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