George D. Webster Jr., M.D., F.A.C.P.; William Siegel, M.D.; Emanuel G. Tulsky, M.D.
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Idiopathic edema is a syndrome of obscure and perhaps diverse etiologies. It is characterized by edema formation, frequently cyclic in nature, occurring almost exclusively in women and not related to detectable parenchymal disease of the cardiovascular, renal, or endocrine systems. Its milder forms merge with the fluid retention associated with the menstrual cycle. Physiologic studies in these patients are relatively few; excessive aldosterone production and an inability to excrete a standard water load have been described, and posture, environmental temperature, and psychic stress have been found to play a role.
The present studies were undertaken to assess the role of
Webster GD, Siegel W, Tulsky EG. Whole Body Hematocrit in Women with Idiopathic Edema: Evidence of an Abnormal Plasma Distribution.. Ann Intern Med. 1965;63:921. doi: 10.7326/0003-4819-63-5-921_2
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Published: Ann Intern Med. 1965;63(5):921.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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