HELEN I. GLUECK, M.D., F.A.C.P.; WALTER ROEHLL JR., M.D.
This paper reports the occurrence of a myocardial infarction in a patient with an absolute deficiency of the Hageman factor (XII). Myocardial infarction has been described in two patients with hemophilia (VIII) (1, 2) and in a third, widespread atherosclerosis was found at autopsy (3). Likewise, myocardial infarction has recently been reported in a patient with plasma thromboplastin component (PTC) (IX) deficiency (4). To our knowledge, such an episode has not been reported in a patient with the Hageman defect. The simultaneous occurrence of these two disorders is of particular interest, since normally in vitro Hageman factor must be activated
GLUECK HI, ROEHLL W. Myocardial Infarction in a Patient with a Hageman (Factor XII) Defect. Ann Intern Med. ;64:390–396. doi: 10.7326/0003-4819-64-2-390
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Published: Ann Intern Med. 1966;64(2):390-396.
Acute Coronary Syndromes, Cardiology, Coronary Heart Disease, Emergency Medicine.
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