NATHANIEL I. BERLIN, M.D.; EUGENE J. VAN SCOTT, M.D.; WILLIAM E. CLENDENNING, M.D.; HOWELL O. ARCHARD, D.D.S.; JEROME B. BLOCK, M.D.; CARL J. WITKOP, D.D.S.; HARLEY A. HAYNES, M.D.
Dr. Nathaniel I. Berlin: This discussion of the basal cell nevus syndrome is presented by the National Cancer Institute.
This syndrome was first described by Binkley in 1951, and since that time approximately 100 patients have been described. This rare disorder is characterized by multiple basal cell tumors of the skin, cysts of the jaw, abnormalities of the ribs and metacarpal bones, and several endocrine abnormalities. Response to intravenous administration of parathyroid extract is diminished. Considerable evidence indicates that this is a heritable disorder, and that it may be related to other neoplasms. It is a progressive disorder, and the
BERLIN NI, VAN SCOTT EJ, CLENDENNING WE, ARCHARD HO, BLOCK JB, WITKOP CJ, et al. Basal Cell Nevus Syndrome: Combined Clinical Staff Conference at the National Institutes of Health. Ann Intern Med. ;64:403–421. doi: 10.7326/0003-4819-64-2-403
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Published: Ann Intern Med. 1966;64(2):403-421.
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