GUNNAR BENDIXEN, M.D.
The word hypersensitivity in this paper indicates a state of specifically altered reactivity depending on an antigen-antibody reaction. According to this definition hypersensitivity covers a wide range of conditions corresponding to the concept of allergy as proposed by von Pirquet (1). As the word allergy has gradually lost its specific significance, it will not be used here.
To evaluate diseases in which mechanisms of hypersensitivity are in action, a correct understanding of the nature of hypersensitive phenomena is necessary. Hypersensitivity as a basal biological phenomenon has lately attracted much attention in experimental medicine, and much new evidence has been accumulated.
BENDIXEN G. Classification of Hypersensitivity in Relation to Clinical Disease. Ann Intern Med. ;64:668–686. doi: 10.7326/0003-4819-64-3-668
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Published: Ann Intern Med. 1966;64(3):668-686.
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